Nikki and the Lyell unit are called in to investigate an ysgou.cc attack against a transgender man.

　　Thomas and Jack are surprised to see Nikki back at The Lyell, the disappearance of her friend Sally forces her to face her back after her harrowing experience in Mexico.

　　This year Silent Witness celebrates its 20th anniversary with five explosive stories that take the show into new and uncharted territories as well as delving into the murky depths of city life. Five contemporary thrillers that start amongst the familiar landscapes of London and end up in the dusty scrubland of Mexico.

　　Following a court appearance for drunk driving, Leo is required to perform unpaid work as a punishment, assisting AJ, a community worker on a run-down,largely black-occupied housing estate in South London. AJ is hoping to divert boys away from crime by encouraging them to do sports, and, though initially dismissive of Leo as a white intruder, comes to respect him after he has saved the life of Errol, a former gang member now anxious to keep his little brother Levi out of trouble. Errol has been stabbed in the leg by members of a gang from a rival estate and Leo stops him from bleeding to death. Earlier in the week a young girl called Shana Block was stabbed to death at a funfair and her murder recorded on a mobile phone. As Shana lived on the estate police sergeant Wallace involves Leo as a go-between with the suspicious residents. Also on the scene are Harry and Nikki, the latter dating Ryan, a young Scottish paramedic she met when called to the scene of Shana's death.

　　The pathologists investigate when a military helicopter crashes into a refugee detention center. Harry and Nikki actually witnessed the crash and were first on the scene but the case is complex since the center was Ministry of Defense property leased to the Home Office. The team is shocked at the conditions they find in the center and Harry, who has a close friend in the RAF, is shaken when a government Minister attributes the accident to pilot error.

　　When a boat carrying illegal passengers is found crashed in the Thames, the team investigate.

本劇改編自同名小說。26歲的研究生小森冰雨（伊藤健太郎 飾）愛上了比自己大一輪的42歲女性水野伊麻（栗山千明 飾）。超越年齡差異的相互吸引中，冰雨想要跨出一步，伊麻告訴他的是“和兩個戀人一起生活”的事實。在全員同意并相互理解的基礎(chǔ)上貫徹“復(fù)數(shù)戀愛”這一愛的伊麻、對這種愛的形式感到困惑的冰雨、以及伊麻的46歲戀人·風(fēng)間到（丸山智己 飾）和36歲的空久保亞夫（千賀健永 飾）之間不被常識所接受的戀愛模樣，將在本劇中得到刻畫。此外，伊麻的友人·絹香因與道德騷擾的丈夫的關(guān)系而煩惱，伊麻的女兒·千夏等人的故事也糾纏在一起，各自的愛情故事由此展開。