麥可(狄恩肯恩飾)在路上搭載了年輕性感的正妹(克莉絲汀波森飾)，麥可原先認為漫漫公路有正妹相伴艷福不淺，自以為遇上了豔遇的他，卻不知道自己即將陷入一連串的陰謀及殺機，一趟沒有終點的旅程即將展開…
　　故事描述一個男人在路途中載了一位年輕的女人，原來只是好心借人搭便車，結(jié)果男主人公卻發(fā)現(xiàn)自己陷入了一場可怕的午夜夢魘……
　　If she looks too good to be true, then she absolutely is. Just ask Michael Anderson (Dean Cain), a gullible film editor who picks up a sexy young hitchhiker (Christie Burson) in the Arizona desert. After the most thrilling one night stand of his life, Michael becomes embroiled in a twisted love con involving a sadistic crime boss (Michael Madsen), a lonely henchman, and a thieving bank manager. Trust isn't just a bitch, it's a dirty little trick!
　　A crime bosss money is missing and he wants it back by any ay means. The beautiful hitchhiker has it and wants to make the getaway.
　　Alexander "Sasha" Shulgin is the scientist behind more than 200 psychedelic compounds - including MDMA, more commonly known as Ecstasy. Considered to be one of the greatest chemists of the 20th century, Sasha's vast array of discoveries have had a profound impact in the field of psychedelic research, making him a subject of fascination and controversy among fellow scientists and a folk hero to recreational users of psychedelics. Dirty Pictures uncovers the lifework of Dr. Shulgin and takes  viewers inside his Northern California home where he lives with his wife of 40 years and continues to carry out experiments in a makeshift laboratory. Director étienne Sauret likewise delves into the broader world of psychedelic research - where the fields of chemistry, neuroscience and philosophy intersect - and investigates whether or not this particular field could aid in solving the deepest mysteries of the human mind.