第三季將繼續(xù)講述伊芙和維倫內(nèi)爾的故事——她們相互有著殘暴過往，曾經(jīng)深陷對方不可自拔，如今卻竭力維持沒有對方的生活。維倫內(nèi)爾，無人問津的職業(yè)殺手，對她而言伊芙已死；伊芙，大隱隱于市的軍情六處前特工，維倫內(nèi)爾將永遠不會找到她。一切看起來風(fēng)平浪靜，直到一起涉及個人的震驚死亡讓兩人軌跡再次相匯，而這又勢必教她們付出親朋好友乃至各自靈魂的代價。

講述有精神病的刺客（朱迪·科默 飾）與英國安全局人員（吳珊卓 飾）這兩個聰明女人互相對對方著迷，并進行了一場史詩式的貓捉老鼠游戲。

　　This drama is set in a south Florida plastic surgery center, McNamara-Troy, centering around the two doctors who own it. Sean McNamara (Dylan Walsh) is having problems at home, trying to keep his family together, trying to patch up the rocky road him and his wife Julia (Joely Richardson) are experiencing. On the other hand, sex-craved Christian Troy (Julian McMahon) uses his charm to bring in potential female candidates and conducts shady business deals, often for the love of money. While Sean takes his job seriously, he often has to fix Christian's mistakes. During the first season, Sean and Christian got mixed up with Escobar Gallardo, a Colombian drug lord who forced the two to do free surgery whenever he wanted them to. Sean's marriage with Julia began to wear thin, and Sean had an affair with a patient named Megan O'Hara. Julia went back to school, but it was interrupted by a miscarriage of a child Sean and Julia were trying to have. Christian learned he is the father of a baby with a woman named Gina, who he met at Sexaholics Anonymous. When the baby was born, we learn that the baby is African-American, and therefore not his. Julia questions Matt's paternity.